PDEs as drug targets
PDE4NPD and the EU
Cutaneous Leishmaniasis sweeps across the Middle East
20 June 2016
Research published last month in PLOS Neglected Tropical Diseases has found that cutaneous leishmaniasis is sweeping across the Middle East as a combination of heavy conflict and a breakdown of health care facilities in Isis-occupied areas. The diseases currently affects hunderds of thousands of people living in refugee camps or trapped in conflict zones.
Puts 65 million people at risk of infection, with 20,000 new cases annually. Affects the central nervous system, and also inflicts economic damage via infections in cattle.
A parasitic sporadic/epidemic disease infecting more than 12 million people worldwide, causing 20-30,000 deaths each year.
Causes cardiac disorders or digestive alterations in 40% of patients, and can lead to death (7,000 each year) or life-long disability. Chronically infects 6-7 million people.
Affects 78 countries, with 240 million infected people – imposing an economic burden second only to malaria in endemic countries.