PDEs as drug targets
PDE4NPD and the EU
PDE4NPD Vacancy: Experienced Computational Chemist
20 May 2016
IOTA Pharmaceuticals (Cambridge, UK) is looking for an experienced computational chemist to develop a new drug design platform to support its drug discovery programs. The position is funded from the EU Framework 7 programme PDE4NPD, targeting parasitic phosphodiesterases.
Puts 65 million people at risk of infection, with 20,000 new cases annually. Affects the central nervous system, and also inflicts economic damage via infections in cattle.
A parasitic sporadic/epidemic disease infecting more than 12 million people worldwide, causing 20-30,000 deaths each year.
Causes cardiac disorders or digestive alterations in 40% of patients, and can lead to death (7,000 each year) or life-long disability. Chronically infects 6-7 million people.
Affects 78 countries, with 240 million infected people – imposing an economic burden second only to malaria in endemic countries.